Local cancer charity group funds four cancer researchers at UC Santa Cruz

Nikolaos Sgourakis is working to characterize novel targets on neuroblastoma tumors, a type of cancer that affects the development of the sympathetic nervous system in early infants and young children under the age of 10. Because neuroblastoma spreads quickly through the body, the survival rate is less than 50 percent and relapse is common in survivors. The grant will support the Sgourakis lab’s research on a class of proteins displayed by tumor cells for immune surveillance by cytotoxic T cells, which can then eliminate the tumor. 

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New avenues open for the treatment of thrombosis

The new study by researchers from Brazil and the United States describes the Ixolaris structure, an important anticoagulant protein found in tick saliva, and its interaction with Factor Xa, a key enzyme in the process of blood clotting.

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